Database of adverse events associated with drugs and drug combinations
نویسندگان
چکیده
منابع مشابه
Anticoagulation-associated adverse drug events.
PURPOSE Anticoagulant drugs are among the most common medications that cause adverse drug events (ADEs) in hospitalized patients. We performed a 5-year retrospective study at Brigham and Women's Hospital to determine clinical characteristics, types, root causes, and outcomes of anticoagulant-associated ADEs. METHODS We reviewed all inpatient anticoagulant-associated ADEs, including adverse dr...
متن کاملReducing Adverse Events and Hospitalizations Associated with Drug Interactions
A drug-drug interaction is a pharmacokinetic or pharmacodynamic influence of one drug on another, which can reduce the effectiveness of one or both of the interacting drugs or can lead to toxic effects.1 It is estimated that such drug interactions cause up to 2.8% of hospital admissions,2 and they can lead to serious adverse outcomes for patients. One drug combination that has resulted in death...
متن کاملSeizure risk associated with neuroactive drugs: Data from the WHO adverse drug reactions database
PURPOSE To explore the association between the use of neuroactive drugs and reports of epileptic seizures. MATERIAL Using the WHO adverse drug reactions (ADR) database, VigiBase, we surveyed reports of suspected seizures from 1968 until February 2006. Case reports of ADRs, that were classified as convulsions were collected and compared to the total number of ADRs reported. RESULTS The total...
متن کاملUpdate on adverse drug events associated with parenteral iron.
BACKGROUND We previously compared the safety profile of three formulations of intravenous iron used during 1998-2000 and found higher rates of adverse drug events (ADEs) associated with the use of higher molecular weight iron dextran and sodium ferric gluconate complex compared with lower molecular weight iron dextran. Since that time, iron sucrose has become widely available and clinicians hav...
متن کاملAdverse events associated with ERCP.
Vinay Chandrasekhara, MD, Mouen A. Khashab, MD, V. Raman Muthusamy, MD, FASGE, Ruben D. Acosta, MD, Deepak Agrawal, MD, MPH, David H. Bruining, MD, Mohamad A. Eloubeidi, MD, MHS, FASGE, Robert D. Fanelli, MD, FACS, FASGE, SAGES Representative, Ashley L. Faulx, MD, FASGE, Suryakanth R. Gurudu, MD, FASGE, Shivangi Kothari, MD, Jenifer R. Lightdale, MD, MPH, FASGE, NASPGHAN Representative, Bashar ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-56525-5